Human genetics of cardiometabolic disease
Category(ies) of Research
Descriptor of Research
The Stitziel Lab studies human genetic variation underlying Mendelian and complex forms of cardiometabolic disease. We utilize cutting edge next-generation genomic techniques along with traditional model system approaches to map causal disease genes, dissect mechanisms and pathways underlying disease, and apply insights from our studies to improve clinical care and human health. We are currently studying the metabolic effects of ANGPTL3 on glucose and lipid metabolism in humans and the role of SVEP1 in influencing cardiometabolic disease in humans and mice.