Notice of Specialist Interest (NOSI):

Availability of Funds for Competitive Revision Applications to Conduct Research with a Focus in Chronic Disease and the Reduction of Health Disparities Within the Mission of NIDDK (R01, U01, U24, P30, U54)

NOT-DK-20-012
NIDDK

For more information: https://grants.nih.gov/grants/guide/notice-files/NOT-DK-20-012.html


Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required)

PAS-20-160

This Funding Opportunity Announcement encourages the submission of pilot and feasibility clinical trials conducted in humans that will lay the foundation for larger clinical trials related to the prevention and/or treatment of diseases and conditions within the mission of NIDDK. The program will support small, short-term clinical trials in humans to acquire preliminary data regarding the effects of the intervention, as well as feasibility data related to recruitment and retention, and study conduct. Applications for clinical trials submitted under this FOA should have clearly described aims and objectives, and have a high likelihood that the trial findings will lead to more definitive, hypothesis-driven trialsto improve understanding, diagnosis, prevention or treatment of the diseases studied and have the potential to impact clinical practice and/or public health. Preliminary data regarding intervention efficacy are not required.

For more information:  https://grants.nih.gov/grants/guide/pa-files/PAS-20-160.html


Deadline Extended: May 18, 2020

Call for Novel Studies in Diabetes and Obesity
to Eliminate Disparities:
Team Science Across the Translational Continuum

Washington University Center for Diabetes Translation Research (CDTR),
Nutrition Obesity Research Center (NORC), Diabetes Research Center (DRC),
Institute of Clinical and Translational Sciences (ICTS), and Institute for Public Health (IPH)

The major objective of this rapid funding mechanism is to stimulate transdisciplinary team research to advance novel approaches in the prevention and treatment of diabetes/obesity with the goal of eliminating disparities. This opportunity will support novel research directions targeting the interaction of social determinants with biological and environmental mechanisms through which social disadvantage increases diabetes/obesity burden and inform new leverage points for intervention.

Awards will provide up to $60,000 direct costs, per year, for one or two years. The second year of funding will depend on demonstrating adequate progress during the first year. Preference will be given to projects focusing primarily on the St. Louis region.

Application timeline:
• Electronic notification of intent due by May 4, 2020 (optional)
• Full proposals are due May 18, 2020 (5:00pm)

Additional application details are attached and can be found at https://cdtr.wustl.edu/pilot-feasibility/special-request-for-applications/.

For more information contact Allison Phad, CDTR Research Manager, at allisonphad@wustl.edu.


Patient-oriented Research to Mitigate Health Disparities and Lessen the Burden of Chronic Diseases Within the Mission of NIDDK (R01 Clinical Trial Optional)

(RFA-DK-20-015)

Application Receipt Date(s): May 22, 2020 No late applications will be accepted for this Funding Opportunity Announcement.

https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-20-015.html


Shared Instrumentation for Animal Research (SIFAR) Grant Program (S10 Clinical Trial Not Allowed)

(PAR-20-112)
Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs

Application Receipt Date(s): June 1, 2020

https://grants.nih.gov/grants/guide/pa-files/PAR-20-112.html


Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

(PAR-20-113)
Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs
National Institute of General Medical Sciences

Application Receipt Date(s): June 1, 2020

https://grants.nih.gov/grants/guide/pa-files/PAR-20-113.html


High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)

(PAR-20-114)
Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs
National Institute of General Medical Sciences

Application Receipt Date(s): June 1, 2020

https://grants.nih.gov/grants/guide/pa-files/PAR-20-114.html


The 2020 DiaComp Pilot & Feasibility Program

Applications of 5 pages requesting up to $100,000 for one year are due June 10, 2020.

Current areas of interest include, but are not limited to:

• Role of the Microbiome in Diabetic Complications

• Targeted Delivery of Therapeutics

• Imaging and Tissue Interrogation

• Sex Differences

• Autonomic Neuropathy

• Pre-clinical Testing

Who is eligible to apply?

Applications are accepted from domestic (US) institutions/ organizations.
Non‐domestic (non‐U.S.) Entities (Foreign Institutions) are NOT eligible to apply.

What funds are available for P&F Projects?

Applicants may request up to $100,000 (direct + indirect costs) Total Costs for one year. The number of awards will depend upon the number, quality, duration, and cost of the applications received. Awards will be made as subcontracts from the DiaComp Coordinating Unit (CU) at Augusta University and NOT directly by the NIH.

Timetable for P&F Application Submissions.

June 10th Deadline for applications submitted to the DiaComp CU.
Oct. 1st Estimated Start Date for DiaComp P&F Project funding.

Contact Information

For more detailed information, please go to http://www.diacomp.org/shared/pilotFeasibility.aspx


dkNET New Investigator Pilot Program in Bioinformatics

Key Dates

Posted Date November 01, 2019

Letter of Intent Due Date January 14, 2020

Application Due Date February 14, 2020

Scientific Review March-April 2020

Start Date May 2020

Expiration Date February 15, 2020

Submission Site

For further information and submission instructions please go to the MMPC submissions portal.

Introduction

As high throughput technologies become routine for individual laboratories in biomedical research, there is a growing need to develop a workforce that can use and further refine the computational approaches needed to interrogate complex data. This pilot program, through the NIDDK Information Network (dkNET), is designed to encourage new investigators to apply innovative bioinformatics approaches to important research problems in Diabetes, Endocrinology and Metabolic Diseases (DEMD). The dkNET New Investigator Pilot Program is designed to: (i) facilitate the ability of Early Stage and New Investigators with computational and bioinformatics expertise to pursue research questions in DEMD, or (ii) allow Early Stage and New PIs currently pursuing DEMD-related research to explore incorporating computational, statistical, and/or bioinformatics approaches into their research projects.


NIDDK Funding Opportunity Announcements

Bioinformatics Interdisciplinary Predoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases (F31)
(PAR-19-378)
National Institute of Diabetes and Digestive and Kidney Diseases
Application Receipt Date(s): Standard dates apply All applications are due, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Bioinformatics Interdisciplinary Postdoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases (F32)
(PAR-19-379)
National Institute of Diabetes and Digestive and Kidney Diseases
Application Receipt Date(s): Standard dates apply All applications are due, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.


Notice of Special Interest: Alzheimer’s-focused administrative supplements for NIH/NIDDK grants that are not focused on Alzheimer’s disease

Notice Number:

NOT-DK-20-009

For details, see:  https://grants.nih.gov/grants/guide/notice-files/NOT-DK-20-009.html

Active awards with project end dates in FY 2021 or later are eligible. The award may not be in terminal no cost extension or going into no cost extension in FY 2020.   As administrative supplements, the work proposed needs to be within the scope of the research or training that is already supported.

Application due date:  March 6, 2020 by 5:00 PM local time of applicant organization.  To be considered for funding, applicants must carefully follow the application instructions in the NOSI.

Applications for this initiative must be submitted using PA-18-591 Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional).


Workshop on the Physiology of the Weight Reduced State

Workshop on the Physiology of the Weight Reduced State
June 3 – 4, 2019
Bethesda, MD

Background

Preventing regain of lost weight is the most difficult challenge in the treatment of obesity. Various physiological adaptations occur that make maintaining weight loss difficult by reducing energy expenditure and increasing energy intake.

Objectives

The overarching goal of this workshop is to explore the mechanisms and integrative physiology of adaptations in appetite, energy expenditure, and thermogenesis (metabolic adaptation) that occur in the weight reduced state and may oppose weight loss maintenance.

The workshop will include—

  • Clinical experience with weight reduction and weight loss maintenance versus regain across interventions
  • Factors opposing weight loss maintenance
  • Factors affecting energy intake in the weight reduced state, including neural and endocrine regulation and the integration of homeostatic and hedonic pathways along with microbiome links
  • Metabolic adaptation/adaptive thermogenesis and tissue-specific roles and mechanisms
  • Strategies for understanding the physiology of the weight reduced state and improving weight loss maintenance
  • Factors potentially responsible for physiological variability in weight maintenance versus regain

Registration Deadline

May 25, 2019